Please select a CNS region and cell type to see the top 50 genes ranked by expression fidelity, along with associated data on absolute expression levels, loss-of-function (LoF) mutation intolerance, literature citations, and protein-protein interactions.
Expression fidelity (blue track) is a z-score
that quantifies the extent to which the expression pattern
of each gene was correlated with the inferred abundance of
the cell type over all queried samples.
CNS expression (red track) is an average of the
expression percentile ranks of each gene over all queried CNS
LoF intolerance (black track) is the probability
that a given gene is intolerant to loss-of-function (LoF)
mutations. Data are from the Exome Aggregation Consortium.
PubMed citations (green track) is the number of
citations in PubMed returned by queries for each gene symbol
plus the name of the cell type.
PPI (interior lines) denote
protein-protein interactions (PPI) from the