Cell types

Please select a CNS region and cell type to see the top 50 genes ranked by expression fidelity, along with associated data on absolute expression levels, loss-of-function (LoF) mutation intolerance, literature citations, and protein-protein interactions.

Species: CNS region: Cell type: Datasets: Samples:

  • Expression fidelity (blue track) is a z-score that quantifies the extent to which the expression pattern of each gene was correlated with the inferred abundance of the cell type over all queried samples.

  • CNS expression (red track) is an average of the expression percentile ranks of each gene over all queried CNS regional datasets.

  • LoF intolerance (black track) is the probability that a given gene is intolerant to loss-of-function (LoF) mutations. Data are from the Exome Aggregation Consortium.

  • PubMed citations (green track) is the number of citations in PubMed returned by queries for each gene symbol plus the name of the cell type.

  • PPI (interior lines) denote protein-protein interactions (PPI) from the STRING database.